This protocol collection explains how to build a low-cost, lightweight system to implant 1 Neuropixels 1.0 probe or 2 Neuropixels 2.0 probes into mice, record during freely moving behavior, then recover the probes for future use.
iElectrodes is an open-source Matlab toolbox to localize intracranial electrodes from MRI and CT images. Atlas and brain surfaces can be easily loaded for anatomical labeling. The toolbox is capable of working with ECoG (subdural grids and strips) and SEEG (depth) electrodes.
Reading directions vary across writing systems. Through long-term experience readers adjust their visual systems to the dominant reading direction in their writing systems. However, little is known about the neural correlates underlying these adjustments because different writing systems do not just differ in reading direction, but also regarding visual and linguistic properties.
DataJoint Elements is a growing compilation of community-curated, open-source software modules for building automated data pipelines and analysis workflows for neuroscience experiments. DataJoint Elements enables: Secure tracking of animal subjects, equipment, and procedures Automatic data ingestion Customized research workflows Faster deployment Improved reproducibility Greater continuity across projects Secure tracking.
A search for magnetosensitive neurons Many species across the animal kingdom are said to use the Earth’s magnetic field for orientation and navigation. However, the mechanisms by which information about magnetic fields enters the nervous system remain unknown.
Video capture is increasingly necessary for neuroscience research where neural and behavioral data are synchronized to reveal correlative and causal relationships. This relies on a recording system that can capture quality videos without significant alterations to preexisting experimental conditions (e.
DataJoint Core is an open-source toolkit for defining and operating computational data pipelines (i.e., sequences of steps for data acquisition, processing, and transformation). Pipelines built in DataJoint Core offer: Efficient design with intuitive queries Automated, reproducible computation with full referential integrity Coordination of multiple human and computer workers Flexibility to adapt and change DataJoint Core includes libraries for Python and MATLAB, a REST API, and GUI tools for data entry and visualizations.
SqueakR is an open-source R package, available on CRAN, which streamlines bioacoustics research through automated data processing and visualizations for rodent vocalizations exported from DeepSqueak. These functions are harnessed through the ‘SqueakR’ Shiny Dashboard, available as a function within the package, which can be used to visualize experimental results and analyses, as well as conduct statistical significance test between call features across groups.
While accurate behavioral state classification is critical for many research applications, it is often done manually, which can be both tedious and inaccurate. Here we present a novel artificial neural network that uses electrophysiological features to automatically classify behavioral state in rats with high accuracy, sensitivity, and specificity.