This simple optogenetics stimulation driver is based on the Arduino Uno, and produces millisecond-accurate timing to control a single laser or LED. The dials allow easy control of pulse on-time and frequency, with a simple switch to turn the flashing on or off.
Automated microscope slide stainers are typically very expensive, and unless the lab performs heavy histological work it is hard to justify buying a €2000-€10000 machine. As a result, histology and pathology labs around the world lose thousands of working hours for following a procedure that could be easily automated.
Controlling biological processes using light has increased the accuracy and speed with which researchers can manipulate many biological processes. Optical control allows for an unprecedented ability to dissect function and holds the potential for enabling novel genetic therapies.
Autopilot is a Python framework for performing complex, hardware-intensive behavioral experiments with swarms of networked Raspberry Pis. As a tool, it provides researchers with a toolkit of flexible modules to design experiments without rigid programming & API limitations.
We made a low-cost centrifuge that can be useful for carrying out low-cost LAMP based detection of SARS-Cov2 virus in saliva. The 3D printed centrifuge (Mobilefuge) is portable, robust, stable, safe, easy to build and operate.
The PocketPCR is a so called thermocycler used to activate biological reactions. To do so the device raises and lowers the temperature of the liquid in the small tubes. The polymerase chain reaction (PCR) is a method widely used in molecular biology to make copies of a specific DNA segment.
PiDose is an open-source tool for scientists performing drug administration experiments with mice. It allows for automated daily oral dosing of mice over long time periods (weeks to months) without the need for experimenter interaction and handling.
OpenDrop a modular, open source digital microfludics platform for research purposes. The device uses recent electro-wetting technology to control small droplets of liquids. Potential applications are lab on a chip devices for automating processes of digital biology.
Stytra, a flexible, open-source software package, written in Python and designed to cover all the general requirements involved in larval zebrafish behavioral experiments.
It provides timed stimulus presentation, interfacing with external devices and simultaneous real-time tracking of behavioral parameters such as position, orientation, tail and eye motion in both freely-swimming and head-restrained preparations.
The fruit fly, Drosophila melanogaster, continues to be one of the most widely used model organisms in biomedical research.
Though chosen for its ease of husbandry, maintaining large numbers of stocks of fruit flies, as done by many laboratories, is labour-intensive.